CONSISTENT PATTERN OF EPIDEMIC SLOWING ACROSS MANY GEOGRAPHIES LED TO LONGER, FLATTER INITIAL WAVES OF THE COVID-19 PANDEMIC.

Consistent pattern of epidemic slowing across many geographies led to longer, flatter initial waves of the COVID-19 pandemic.

To define appropriate planning scenarios for future pandemics of respiratory pathogens, it is important to understand the initial transmission dynamics of COVID-19 during 2020.Here, we fit an age-stratified compartmental model with a flexible underlying transmission term to daily COVID-19 death data from Arm Chair (set of 4) states in the contiguou

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Synthesis of Altissimacoumarin D and Other Prenylated Coumarins and Their Ability to Reverse the Multidrug Resistance Phenotype in Candida albicans

Azoles are the main antifungal agents employed in clinical practice to treat invasive candidiasis.Nonetheless, their efficacy is limited by fungal resistance mechanisms, mainly the overexpression of efflux pumps.Consequently, candidiasis has a worrisome death rate of 75%.One potential strategy to overcome efflux-mediated resistance is to inhibit th

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